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產(chǎn)品展示您現(xiàn)在的位置: 首頁 > 產(chǎn)品展示 > > 美國戴安Dionex > 美國戴安 P/N: 074188Dionex Acclaim Trinity P1 Series 液相色譜柱

Dionex Acclaim Trinity P1 Series 液相色譜柱

簡要描述：

戴安公司生產(chǎn)的儀器主要有離子色譜儀、高效液相色譜儀、快速溶劑萃取儀和氨基酸直接分析儀。其中離子色譜儀憑借著雄厚的技術(shù)優(yōu)勢和方法已廣泛地應(yīng)用于各個領(lǐng)域，其*達80%。與離子色譜相關(guān)的文章有90%均出自戴安公司生產(chǎn)的離子色譜儀。

型號 美國戴安 P/N: 074188
廠商性質(zhì) 代理商
更新日期 2018-04-23

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

  • Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
  • Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
  • Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
  • Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

  • Active pharmaceutical ingredients (API) and counterions (cations or anions)
  • Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
  • Mixture of acidic and basic drug substances and respective counterions
  • Drug substances of acidic, basic, and neutral mixtures
  • High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技術(shù)參數(shù)：


Acclaim Trinity P1 Column – Superior Performance for Pharmaceutical Applications Specifications
Column chemistrySCX, WAX and RP Mixed-Mode
Operating pressure limit (recommended)4500 psi (4000 psi)
Operating pH range (recommended)2.5 – 7.0 (3.0 to 6.2)
Operating flow rate range (recommended)0.3 – 1.5(0.4 – 0.8) mL/min for 3.0-mm i.d. formats
0.15 – 0.80 (0.2 to 0.4) mL/min for 2.1-mm i.d. formats

訂購信息：



Analytical Columns
Acclaim Trinity P1, 3μm, 3.0 x 150mm075563
Acclaim Trinity P1, 3μm Analytical, (3.0 x 100mm)071387
Acclaim Trinity P1, 3μm Analytical, (3.0 x 50mm)071388
Acclaim Trinity P1, 3μm, 2.1 x 150mm075564
Acclaim Trinity P1, 3μm Analytical, (2.1 x 100mm)071389
Acclaim Trinity P1, 3μm, 2.1 x 50mm075565
Guard Columns
Acclaim Trinity P1, 3μm Guard Cartridges, (3.0 x 10mm), 2ea (Use Holder V-2)071390
Acclaim Trinity P1, 3μm Guard Cartridges, (2.1 x 10mm), 2ea (Use Holder V-2)071391
Acclaim SST Guard Cartridge Holder V-2069580
Acclaim Guard Kit (Holder and coupler) V-2069707
Guard to Analytical Column Coupler V-2074188


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